Clinical trials and drug development for gluten sensitivity and wheat allergies

The idea is to evaluate if the so called "Gluten Sensitivity" is a real clinical entity. Gluten sensitive (GS) persons are defined as those patients, being neither celiac or allergic to weat, who develop symptoms following gluten consumption.

ClinicalTrials.gov
A comprehensive listing of clinical trials (both government and industry sponsored) conducted across the U.S. Use key terms "celiac disease" or" gluten sensitivity".

The Beyond Celiac Clinical Trials Resource Center
Beyond Celiac Clinical Trials Resource Center, presented in partnership with CenterWatch, the leading publisher of information on clinical research for patients and their advocates and healthcare professionals.

Celiac Disease Drug Development in the News
Read updates from the research field, including calls for enrollment in clinical trials, results from previous celiac disease trials, and advances in funding for continued research.

Drug Development

Larazotide acetate, (Alba Therapuetics) is a drug currently in development that works by inhibiting zonulin, which has been shown to increase the permeability of the gut in celiac disease, allowing gluten particles to pass through to trigger inflammation, and gastrointestinal and other symptoms. Larazotide acetate is a novel agent that belongs to a new class of drugs called tight junction regulators. It is a synthetic eight amino acid peptide that has the sequence GGVLVQPG.